News

August 18, 2017August 18, 2017

Kidney Function Decline May Not Be Good Indicator of Trial Outcomes in Alport Syndrome Patients, Study Suggests

The rate at which patients with Alport syndrome lose their kidney function varies widely between patients and even within the same individual, according to a study in the Canadian Journal ... Read more

August 16, 2017August 16, 2017

Facebook Video That Led to Mom Getting New Kidney Also Spotlights Living Donor Program

News

Since a Pennsylvania mother of two underwent a kidney transplant, whose donation was due to a video that her children had posted on Facebook, the National Kidney Registry’s (NKR) Paired Exchange Donation program ... Read more

August 14, 2017

Early Inflammation Could Drive Both ADTKD and Alport Syndrome Kidney Disease, Study Suggests

News

Early inflammation probably contributes to the tissue scarring and kidney damage seen in autosomal dominant tubulointerstitial kidney disease, according to an Italian study noting that the same thing occurs ... Read more

August 11, 2017August 11, 2017

Genetic Testing Could Help Doctors Make Alport Syndrome Diagnosis, Study Reports

News

Genetic testing of patients with symptoms suggesting Alport syndrome could help doctors make a definitive diagnosis, a study reports. The tests could also identify genetic errors associated with the ... Read more

August 9, 2017

Reata Starts Phase 3 Portion of Trial of Bardoxolone Methyl for Kidney Disease Due to Alport Syndrome

News

Reata Pharmaceuticals has enrolled the first patient in the Phase 3 portion of a clinical trial evaluating bardoxolone methyl as a treatment for chronic kidney disease stemming from Alport syndrome. ... Read more

August 7, 2017

Loss of Specialized Kidney Cells Accelerated in Alport Patients, Study Shows

News

Alport syndrome (AS) patients lose specialized kidney cells, called podocytes, 11 times faster than healthy people, according to a new study. The phenomenon seems to underlie disease progression and can ... Read more

August 4, 2017August 4, 2017

Therapy for Alport Syndrome Advancing after Stock Sale, Reata Pharmaceuticals Announces

News

Reata Pharmaceuticals is expecting $115.9 million revenue from the public offering of some of its stock shares, which will support the clinical development of the company’s leading investigational therapy, bardoxolone methyl, for chronic ... Read more

July 26, 2017

Reata’s Bardoxolone for Alport Enters Phase 3 Trial After Improvements Seen in Phase 2

News

The Phase 2 portion of a clinical trial exploring Reata Pharmaceuticals’ bardoxolone methyl in patients with chronic kidney disease caused by Alport syndrome showed convincing results, allowing researchers to ... Read more

July 21, 2017July 21, 2017

Researchers Urge Genetic Testing for Autosomal Dominant Alport Syndrome

News

A significant number of patients with a family history of kidney disease that was difficult to diagnose have autosomal dominant Alport syndrome, according to a study from Japan. The ... Read more

July 19, 2017

Children’s Viral Video Plea to Find Kidney Donor for Mom Has Happy Ending

News

Diana Zippay, from Monongahela, Pennsylvania, and diagnosed with Alport Syndrome, recently announced on her Facebook page that she has found a lifesaving kidney donor and soon will receive the ... Read more