News

A research funding program run by the Alport Syndrome Foundation (ASF), the Pedersen family and the Kidney Foundation of Canada has awarded two researchers $100,000 each to advance projects on Alport syndrome. The program supports studies that seek new ways to prevent kidney damage and hearing loss in Alport patients. It places emphasis on research to identify and…

Bromide supplementation might be harmful to Alport syndrome patients if the findings of a study in mice translate into human settings. Researchers at Kumamoto University in Japan found that giving bromide to Alport mice worsened their disease. The results countered an earlier study noting that bromide is a trace element required…

Researchers have identified two mutations of the COL4A3 gene that appear to be linked to the development of a mild form of autosomal recessive Alport syndrome, or ARAS. The study, “A case of mild phenotype Alport syndrome caused by COL4A3 mutations,” was published in the journal CEN Case Reports.

A protein receptor that is activated in the early phase of chronic kidney disease contributes to the development of bone, cardiac and kidney dysfunction, according to a study using a mouse model of Alport syndrome. The title of the research was “The activin receptor is stimulated in the skeleton,…

A rare case of combined Alport syndrome and rapidly progressing membranous nephropathy, another kidney disease that affects the kidneys’ filtering mechanism, has prompted researchers to further explore whether the two conditions are related. Other factors, such as infectious disease, could also trigger additional kidney issues in Alport patients, researchers from…

The Alport Syndrome Foundation is inviting young people with the disease to apply for an award that allows them to pursue an activity or complete a project. November 3 is the deadline for applying for the 2018 Paul Silver Tribute Award, which is aimed at enriching the lives of Alport patients…

Researchers at Florida’s University of Miami (UM) and the University of Cyprus in Nicosia have received $100,000 each to continue research on Alport syndrome. Both studies aim not only to shed light into the underlying mechanism of this disease, but also to help identify potential cures. The funding program is a collaboration among the Alport Syndrome…

The rate at which patients with Alport syndrome lose their kidney function varies widely between patients and even within the same individual, according to a study in the Canadian Journal of Kidney Health and Disease. This insight is crucial when studying potential interventions in clinical trials, which tend to observe…

Since a Pennsylvania mother of two underwent a kidney transplant, whose donation was due to a video that her children had posted on Facebook, the National Kidney Registry’s (NKR) Paired Exchange Donation program has been gaining increasing attention. Diana Zippay, 36, began to lose kidney function as a result of her Alport…

Early inflammation probably contributes to the tissue scarring and kidney damage seen in autosomal dominant tubulointerstitial kidney disease, according to an Italian study noting that the same thing occurs in Alport syndrome. Researchers reported that the inflammation they found in animal models of ADTKD has also been seen in mouse…