Author Archives: Özge Özkaya, PhD

Stem Cell Therapy Improves Kidney Function in Mice Model of Alport Syndrome

Chorionic stem cells are able to differentiate into a specialized type of kidney cells both in the laboratory and when injected into the abdomen of a mouse model of Alport syndrome, showed a study published in the scientific journal Stem Cells and Development. This means that chorionic stem cells may offer hope for Alport syndrome patients in the future by delaying the development of kidney disease or even treating the condition by replacing defective kidney cells.

Reducing Podocyte Depletion in Alport Syndrome Could Prolong Kidney Survival

Podocyte depletion might be driving the progression of both Alport syndrome and thin glomerular basement membrane disease (TGBM), according to a study published in the scientific journal PLOS One. Therefore measuring podocyte density in kidney biopsies could provide a quantitative readout describing the risk of progression of the conditions event before pathologic changes appear. Moreover, reducing podocyte depletion could have therapeutic effects in Alport syndrome.